KEGG   NETWORK: N01891
Entry
N01891                      Network                                
Name
GABAA receptor trafficking
Definition
(GABR+(GABARAP+GABARAPL1+GABARAPL2)+NSF) -> (GABR+TRAK2+PLCL1)
  Expanded
((2554,2555,2556,2557,2558,2559)+(2560,2561,2562)+(2565,2566,2567)+(11337+23710+11345)+4905) -> ((2554,2555,2556,2557,2558,2559)+(2560,2561,2562)+(2565,2566,2567)+66008+5334)
Class
nt06544 Neuroactive ligand signaling
Type
Reference
Pathway
hsa04727  GABAergic synapse
Gene
2554  GABRA1; gamma-aminobutyric acid type A receptor subunit alpha1
2555  GABRA2; gamma-aminobutyric acid type A receptor subunit alpha2
2556  GABRA3; gamma-aminobutyric acid type A receptor subunit alpha3
2557  GABRA4; gamma-aminobutyric acid type A receptor subunit alpha4
2558  GABRA5; gamma-aminobutyric acid type A receptor subunit alpha5
2559  GABRA6; gamma-aminobutyric acid type A receptor subunit alpha6
2560  GABRB1; gamma-aminobutyric acid type A receptor subunit beta1
2561  GABRB2; gamma-aminobutyric acid type A receptor subunit beta2
2562  GABRB3; gamma-aminobutyric acid type A receptor subunit beta3
2565  GABRG1; gamma-aminobutyric acid type A receptor subunit gamma1
2566  GABRG2; gamma-aminobutyric acid type A receptor subunit gamma2
2567  GABRG3; gamma-aminobutyric acid type A receptor subunit gamma3
11337  GABARAP; GABA type A receptor-associated protein
23710  GABARAPL1; GABA type A receptor associated protein like 1
11345  GABARAPL2; GABA type A receptor associated protein like 2
4905  NSF; N-ethylmaleimide sensitive factor, vesicle fusing ATPase
66008  TRAK2; trafficking kinesin protein 2
5334  PLCL1; phospholipase C like 1 (inactive)
Reference
PMID:19374920
  Authors
Arancibia-Carcamo IL, Kittler JT
  Title
Regulation of GABA(A) receptor membrane trafficking and synaptic localization.
  Journal
Pharmacol Ther 123:17-31 (2009)
DOI:10.1016/j.pharmthera.2009.03.012
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